Cardura

Cardura is the brand name for doxazosin, an alpha-1 adrenergic receptor blocker used in the treatment of hypertension and benign prostatic hyperplasia (BPH). By blocking the alpha-1 receptors found in vascular smooth muscle, Cardura induces vasodilation, leading to a reduction in blood pressure. Additionally, its ability to relax smooth muscle in the prostate and bladder neck helps alleviate urinary symptoms associated with BPH.

The mechanism of action of Cardura centers on its antagonism of alpha-1 receptors, which normally mediate vasoconstriction. When these receptors are blocked, blood vessels dilate, resulting in decreased peripheral resistance and lower blood pressure. This vasodilatory effect is particularly beneficial for patients with hypertension who may not respond adequately to other classes of blood pressure–lowering medications. The same receptor blockade in the urinary tract facilitates improved urine flow in men with BPH.

Clinically, Cardura is administered orally, usually once daily, with the dosing individualized based on the patient's blood pressure and symptom severity. For hypertension, doses are titrated carefully to achieve the desired reduction in blood pressure while minimizing side effects. When used for BPH, Cardura can help relieve symptoms such as difficulty starting urination, weak stream, and frequent nighttime urination, thereby improving quality of life.

Common side effects of Cardura include dizziness, fatigue, and sometimes orthostatic hypotension—a sudden drop in blood pressure upon standing. Because of its blood pressure–lowering effects, patients are advised to rise slowly from a seated or lying position to minimize the risk of dizziness or fainting. In most cases, these side effects are mild and can be managed with dose adjustments and careful monitoring.

Overall, Cardura offers an effective and well-tolerated treatment option for both hypertension and BPH. Its dual benefits in reducing blood pressure and improving urinary symptoms make it a valuable medication for older adults, who often experience both conditions simultaneously. With appropriate dosing and regular follow-up with healthcare providers, Cardura can help achieve improved cardiovascular and urologic outcomes, enhancing patient comfort and overall quality of life.


NOTE: The above information is for marketing purposes only and is not to be construed as medical advice. Seek advice for medications from a qualified physician.